Basic Information
VIS ID
TVIS10001660
Fusion event
HBV-MIR4435-2HG integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
112147152/111389575 (Hg38)
End
112147152/111389575 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
MIR4435-2HG
Nearest miRNA
hsa-mir-1285-2/Upstream/68489; hsa-mir-10b/Downstream/381486;
Nearest TSS
ENST00000437798/Upstream/22050; ENST00000455309/Downstream/41333;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/164817, chr2-CpG: 63/Downstream/494185
Upstream sequence
cctcatgagtagctgggactacaggtgtgcacctccacaccctgctaattttcttttcttttcttttcttttctttctttctttcttttttttttttttt
Downstream sequence
ttttttttttttgagacacagtctctctctgtcgcctgcccaggctggagagcagtggcgtgatctcggctcactgaaacctccacctcctgggttcaag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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