Basic Information
VIS ID
TVIS10001663
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
123334568/122322329 (Hg38)
End
123334568/122322329 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/2997064; hsa-mir-10400/Downstream/893459;
Nearest TSS
ENST00000518652/Upstream/195145; ENST00000607393/Downstream/106222;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/682180, chr8-CpG: 223/Downstream/457801
Nearby gene
HAS2-AS1(-677004) ; ZHX2(+459333) ;
Nearest cancer related gene
ZHX2(TSG, +459333) ;
Upstream sequence
actctggatctaatgtaaaccttttgttttagctggcttttttttttgacaccactctggcagtgaaagtggggtgtgctgcctcatcattaccaagtag
Downstream sequence
ctgggcgcagtggctcacgcctgtaatcccagcactttgggagttcgagaccagcctggccaacatggtgaaacccggtctctactaaaaatacaaaaat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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