Basic Information
VIS ID
TVIS10001674
Fusion event
HBV-chr17 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1834192/1930898 (Hg38)
End
1834192/1930898 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-22/Upstream/216911; hsa-mir-10226/Downstream/119010;
Nearest TSS
ENST00000595228/Upstream/39248; ENST00000574520/Downstream/64716;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/22095, chr17-CpG: 19/Downstream/3395
Nearby gene
RPA1(-31344) ; RTN4RL1(+3779) ;
Nearest cancer related gene
RPA1(TSG, -31344) ;
Upstream sequence
TCACCTCATGGGCTCTTCAGGGCCCAGACTCCCCTGCCTTCAGCAGCCCTCTCTGGAGAGACCGGCAGGACCGCGCGAGGGAGGGTGCTCAGGTGGCCAT
Downstream sequence
GCGACGCGCCGAGCCTCTCTTCTTTTCCCGGCTTTTTGATTGTGCCGTGAGTTATTTAGCCAACAATAGATGTTTATGTATTTTTTTAGAGCTCATATTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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