Basic Information
VIS ID
TVIS10001679
Fusion event
HBV-DCDC2C integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
3848849/3801259 (Hg38)
End
3848849/3801259 (Hg38)
Location type
Intronic
Target gene
DCDC2C
Nearest miRNA
hsa-mir-10b/Downstream/2173403;
Nearest TSS
ENST00000437798/Upstream/75313; ENST00000451101/Downstream/42925;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/14531, chr2-CpG: 18/Downstream/201800
Upstream sequence
AGTATCGCATCCCAGCAGGACTCACTGAAGGAGGAGTTCCTCAAGCTCTTGCTAATATCCTTGAGTACCAGGTTGTGGACAGAGGTATTGCAGAGCAGGG
Downstream sequence
CGAGAGCAGGTCTGTGCCGCTTCCTGGCTCTGTGACCTATGTACGTAACCTGTCCCAGGCCGTGGCCTTCCTCATTCTTCTGCAAGGGTGACAGCACCCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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