Basic Information
VIS ID
TVIS10001682
Fusion event
HBV-LOC105374894 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
4480311/4480077 (Hg38)
End
4480311/4480077 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA6B
Target gene
LOC105374894
Nearest miRNA
hsa-mir-4645/Upstream/1625970; hsa-mir-10398/Downstream/668156;
Nearest TSS
ENST00000381078/Upstream/133040; ENST00000563079/Downstream/11730;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/198001, chr6-CpG: 179/Downstream/294820
Nearby gene
RPGR(-322692) ;
Upstream sequence
ATACACCCCATTTTGATGTAACGATTTCCCAAGTGGTCCCCAAAATGTCTTTGCAGAGTTGGTTCCTAGAGAACCTCTTAATCAAAACTTAAACTAAATG
Downstream sequence
tcaaagtacgaatctggggagaatgtaaacattcagtccataacaGGCATGCTGCATTTCCCCCGGTTAGGTGCTTTTTTCCCTGGATGGGTAATCCCCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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