AKR1C2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001683
Fusion event
HBV-AKR1C2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
5065439/5023247 (Hg38)
End
5065439/5023247 (Hg38)
Location type
Promoter
Target gene
AKR1C2
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-5699/Upstream/1031988; hsa-mir-107/Downstream/1128949;
Nearest TSS
ENST00000439456/Upstream/5216; ENST00000603312/Downstream/12107;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/196642, chr10-CpG: 54/Downstream/389221
Upstream sequence
gctgcaatgaaggcataatccaaaagcagggtctcccagaagcctcagtggggaatgacctgcttccaaggtcatgggtgactggcagaatccagtgcct
Downstream sequence
tccgggttactggagtgaaggcctcagtttctagctggctgatggccataagccacactcagttcctctcaaagtgggcatgtccacaaggcaattcaTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate