Basic Information
VIS ID
TVIS10001684
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
5560697/5420564 (Hg38)
End
5560697/5420564 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Downstream/554098;
Nearest TSS
ENST00000437798/Upstream/764349; ENST00000322002/Downstream/135467;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1311711, chr2-CpG: 26/Downstream/252786
Nearby gene
SOX11(+272102) ;
Nearest cancer related gene
SOX11(TSG, +272102) ;
Upstream sequence
CAGGTAAAAAAGACACACTAGCAATGATGGGGATCACGTGGAGAGGGAAAGGGTGCAAGAACAAGTACAAAAATATGGAAGTGCAGAGGTCGCCTGGTTC
Downstream sequence
TCAGGGTTCTTAGCAATGAGTTCATTATGATTGGAAAGCAGGGCGGTAGGCAGGGTGATGGAGAGCATGTGACTGGACTGGAAAAGATAGGTCAGAGCCG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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