Basic Information
VIS ID
TVIS10001708
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
30442233/30474456 (Hg38)
End
30442233/30474456 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-3143/Upstream/3326768; hsa-mir-10398/Downstream/109876;
Nearest TSS
ENST00000381078/Upstream/129287; ENST00000484194/Downstream/15011;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/7811, chr6-CpG: 80/Downstream/15136
Nearby gene
TRIM39-RPP21(-127598) ; HLA-E(+14950) ;
Upstream sequence
AGCTGGCCTCCAGAATTGGCAAAATTCTGTGATGTCTCTCTAAATCGAAAATCTATTGTTAAAAACAAACTTCTTTTAAGAGGTTGACTAATTTTTGTGA
Downstream sequence
tccccctccccctccctctccctctccccacagtctccctctccctctctttccacggtctccctctgatgccaagccgaagctggactgtactgctgcc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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