HORMAD2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001709
Fusion event
HBV-HORMAD2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
30518599/30122610 (Hg38)
End
30518599/30122610 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA22B
Target gene
HORMAD2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-580-3p ; hsa-mir-7153-5p ; hsa-mir-103a-2-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p
Nearest miRNA
hsa-mir-1286/Upstream/115497; hsa-let-7a-3/Downstream/608947;
Nearest TSS
ENST00000624155/Upstream/28652; ENST00000447565/Downstream/84499;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/42069, chr22-CpG: 19/Downstream/121130
Upstream sequence
TAATTTTAGGGTTGAAAAATATTCTAGGTATTTATTCATACTCATTGGAAGTATAAATCAGTTCTTGATACTGAGATAATTGGATGGGAGGAGTTGGGGA
Downstream sequence
AGATAAATTTTATGGATAAACCCGAGTCAGCGTGAAAACAAATAATAGTTAACTTCTGGTTATGTGGAGGAAGACAAGCTTTGGGGCTAACTCACTGGGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate