Basic Information
VIS ID
TVIS10001740
Fusion event
HBV-NRDC integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
52310539/51844867 (Hg38)
End
52310539/51844867 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
NRDC
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-181d-5p ; hsa-mir-125b-5p ; hsa-mir-181b-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-12136/Upstream/8465; hsa-mir-101-1/Downstream/2209212;
Nearest TSS
ENST00000473358/Upstream/4413; ENST00000425802/Downstream/33173;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/114718, chr1-CpG: 56/Downstream/33639
Upstream sequence
ggagggaggggggaggggggaaggggaggaggggggagggagggaggaaagaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaagga
Downstream sequence
aggaaggaaggaaggaaggaaaccaaataggctgacagcttgatcttgaacttctagaccccagagctgttatttaagctactctgtctttgatattttg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate