Basic Information
VIS ID
TVIS10001743
Fusion event
HBV-LOC105375835 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
53661850/52749290 (Hg38)
End
53661850/52749290 (Hg38)
Location type
Intronic
Target gene
LOC105375835
Nearest miRNA
hsa-mir-124-1/Upstream/9853015; hsa-mir-10400/Downstream/8965498;
Nearest TSS
ENST00000518652/Upstream/3447; ENST00000331251/Downstream/189141;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/34349, chr8-CpG: 235/Downstream/189851
Nearby gene
RB1CC1(-34824) ; NPBWR1(+190618) ;
Upstream sequence
GTGTAGTTTGTTTTGGCCTGCCTCCCAACTTCTCTAATGTTTCTCTAAAGATCTATTCCTCCTAAATCTTCtttttaaagacttaatttttctagggcag
Downstream sequence
AAATTACTTGAAGACGCCGAAAGCATGAACCTCCATATACACAGAGGGTGGAAAGACCTGGAAGTATCTGGCAAACATGTGTTTGATGACCAGAAAGCAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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