Basic Information
VIS ID
TVIS10001749
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
58148353/57282187 (Hg38)
End
58148353/57282187 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/4569440; hsa-mir-1243/Downstream/3640432;
Nearest TSS
ENST00000502981/Upstream/103042; ENST00000510956/Downstream/143685;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/86238, chr4-CpG: 222/Downstream/3917978
Nearby gene
IGFBP7-AS1(-76888) ;
Upstream sequence
aaaatgctcaacattaataatcaccagaagaatgcaaatcaaaaccacaatgagataccatctcacatcagtcagaatagctattactaaaaagtacaaa
Downstream sequence
AACTTAATTTTAACTTTTATCTTAGAGGACTCAGCTGTACGCCACATATTTAATCTAATCAAGATTGCGCTCAGCACTGCTTTCAGTCCTTGCTGAGAGC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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