Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001755
Fusion event
HBV-C11orf24 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
Start
End
68029550/68262082 (Hg38)
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-7-5p ; hsa-mir-4517 ; hsa-mir-548e-5p ; hsa-mir-16-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-29b-2-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6079 ; hsa-mir-500a-3p ; hsa-mir-5087 ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-767-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3614-5p ; hsa-mir-186-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p
Nearest miRNA
hsa-mir-10392/Upstream/217125; hsa-let-7a-2/Downstream/821094;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/47466, chr11-CpG: 63/Downstream/9750
Upstream sequence
GCCCAGCGGCCCTCTGGGTATATGGCATGGGGCTTGGCTGTGTCGTGGGGGACATGGCCTCCATCTCAGGGATTGGGCTGGTGTGAGGTACTGGCACTGG
Downstream sequence
GCTGGCAGTTGGCTCCCTGGCTTGTGCCTTGGTGGTGGTCACCACTGTGGGGGTGGGGGCGGGCTCTGGGGTTGTGTTTGAGGGCATGGGTGTGGATTTA
Target sequence
CACC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.