ABCB4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001767
Fusion event
HBV-ABCB4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q21.12
Reference genome
GRCh37/hg19
Start
87089249/87459933 (Hg38)
End
87089249/87459933 (Hg38)
Location type
Intronic
Target gene
ABCB4
Nearest miRNA
hsa-mir-10525/Upstream/11544664; hsa-mir-10399/Downstream/4744082;
Nearest TSS
ENST00000635602/Upstream/28433; ENST00000497788/Downstream/15475;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/114161, chr7-CpG: 69/Downstream/15474
Upstream sequence
attctactcccatagttgaacctttcttttgatagagcagtctggaaacactctttttgtcgaatctgcaagtggacatttggagcactttgaaggctat
Downstream sequence
AAAGATAATTTCAAAGTAGGGGCAGTGGAGATATGGTGCTGACAATTCAGGAGTTGGAGAAACGTCTTTGTAGTTTCTTTGATTTTTTTTTTCCAGATGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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