Basic Information
VIS ID
TVIS10001769
Fusion event
HBV-chr16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89075320/89008912 (Hg38)
End
89075320/89008912 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-11401/Upstream/292575;
Nearest TSS
ENST00000527434/Upstream/24880; ENST00000541755/Downstream/44053;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/4416, chr16-CpG: 22/Downstream/33566
Nearby gene
CBFA2T3(-31816) ; ACSF3(+84897) ;
Nearest cancer related gene
CBFA2T3(TSG, -31816) ;
Upstream sequence
CCCACCTCATCTTTGCAGGAGGACCCTGACACACCCACCTCATCTTTGCAGGAGGACCCTGACACACCCACCTCATCTTTGCCAGGAGGACCCGTGACAC
Downstream sequence
ACCCACCTCATCTTTGCCAGGAGGACCCGTGACACACCCACCTCATCTGTGCCAGGAGGACCCTGACACACCCACCTCATCTTTGCAGGAGAACCCTGAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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