Basic Information
VIS ID
TVIS10001778
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
102666324/102049863 (Hg38)
End
102666324/102049863 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2A
Nearest miRNA
hsa-mir-1285-2/Upstream/740329; hsa-mir-10b/Downstream/382426;
Nearest TSS
ENST00000437798/Upstream/26473; ENST00000452403/Downstream/14681;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/351497, chr2-CpG: 92/Downstream/92483
Nearby gene
IL1R2(-21440) ; IL1R1(+20512) ;
Upstream sequence
GCCATGGAAAGAGGCGAGTTTAACTTAAGACAGCTCAGTTTGCATTCATCGTTTGGGAGCCAGTTAAATGGAAGGTGAGGTGGCAGTTGTTAGTGCCGCG
Downstream sequence
TTTGTCAGTGGGTGGCCGAGGATGGTGTCTTGTCCAACTCTGCGGAACTCCGGCTGCTGCTCTGTTAACCCAGCAAGGTCTTCTGGTGGTGGCTGCAGAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate