Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001782
Fusion event
HBV-PIK3CG integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
End
106526831/106886386 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-29b-3p ; hsa-mir-126-3p ; hsa-mir-148b-3p ; hsa-mir-26b-5p ; hsa-mir-27a-3p ; hsa-mir-7-5p ; hsa-mir-10a-5p ; hsa-mir-142-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-4679 ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-410-3p ; hsa-mir-5580-3p ; hsa-mir-511-3p ; hsa-mir-3163 ; hsa-mir-548g-3p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-127-3p ; hsa-mir-196b-5p ; hsa-mir-34a-5p ; hsa-mir-125a-5p ; hsa-mir-26a-5p
Nearest miRNA
hsa-mir-10525/Upstream/4414855; hsa-mir-10399/Downstream/7766959;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/18098, chr7-CpG: 102/Downstream/157982
Upstream sequence
AAAGCCACAAATCTTAAGAAAATACATGTTTAACTGAAATTATAAAGATATTTTGCAAAAAAGGGAAATCGCTCCTGCTGGTGTTTTGTGTATAAATCTC
Downstream sequence
CCAGTCCAGCCTCTACCCCTACCCTCTTCTGGCATGGCCAACCCTACCTCCTCCCTTTCACTTCCATTCATTCCTTTCCCAGGTGCAAAATGACACTTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.