Basic Information
VIS ID
TVIS10001787
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
115986746/116116029 (Hg38)
End
115986746/116116029 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA11G ; FRA11B
Nearest miRNA
hsa-mir-10392/Upstream/2665941; hsa-let-7a-2/Downstream/2527971;
Nearest TSS
ENST00000527297/Upstream/183172; ENST00000439483/Downstream/384601;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/355630, chr11-CpG: 30/Downstream/384513
Nearby gene
LINC00900(-355828) ; BUD13(+632140) ;
Upstream sequence
ttgtttagtctttcctatcactggtttcatataaatgggatcataagaaggtattcttgtatgactgactttgcacagtcaaaatcatgattgtgcaatg
Downstream sequence
tatgcctcagaagttcgttcttttcattgctgagtactattccattatatgcatataccacaaattattgttcataaacacatagactgttttcaatttt
Target sequence
tcagcctcccaagtagctgagattacaggtgtgcaccaccacacctgactaatttttgtatttttagtagagatggggtttcaccacgttggccaggctggtctcgaactcctgacctcaagtgatcctctgcct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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