Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001791
Fusion event
HBV-ADCY5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q21.1
Reference genome
End
123064670/123345823 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1273h-5p ; hsa-mir-718 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6832-3p ; hsa-mir-3922-5p ; hsa-mir-4717-5p ; hsa-mir-4753-5p ; hsa-mir-1249-5p ; hsa-mir-214-5p ; hsa-mir-3616-3p ; hsa-mir-3911 ; hsa-mir-593-5p ; hsa-mir-6514-3p ; hsa-mir-6515-5p ; hsa-mir-6797-5p ; hsa-mir-6811-3p ; hsa-mir-6890-3p ; hsa-mir-7847-3p
Nearest miRNA
hsa-let-7g/Upstream/183944; hsa-mir-12124/Downstream/787106;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/143556, chr3-CpG: 324/Downstream/101548
Upstream sequence
tcctccttgtacctctggtagaattcggctgtgaatccatctggtcttggactctttttggttggtaagctattgattattgccacaatttcagctcctg
Downstream sequence
CTCTGAGTCTCCTGTTAGCCTGAGGGCTCCCCAGACCTCCTTCCCAGATTCCTTGGACACACTCCTTTCTCCTGGGCACGTAAAAACATCTGTCTGGTAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.