Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001793
Fusion event
HBV-HDDC2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
End
125628214/125307068 (Hg38)
Location type
Promoter
Target gene
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-93-5p ; hsa-mir-1303 ; hsa-mir-4474-3p ; hsa-mir-5095 ; hsa-mir-7151-3p ; hsa-mir-3944-5p ; hsa-mir-644a ; hsa-mir-4284 ; hsa-mir-24-3p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-574-5p ; hsa-mir-4518 ; hsa-mir-4693-3p ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-4459 ; hsa-mir-4433b-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4700-3p ; hsa-mir-32-3p
Nearest miRNA
hsa-mir-10398/Upstream/5291811; hsa-mir-1202/Downstream/1177563;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/5097, chr6-CpG: 31/Downstream/56330
Upstream sequence
ctctagatagaagaattctcaaacactgctatgtgatgtttgcattcaagtcacagagtgcaacattcctcttgacagagcagttgggaaacactccttt
Downstream sequence
CAAAGGAGCAGCAGCAGAGTGAACCAAGTCTCTGATGGCTGAGAGTGATGGTGAAGACTTTGCTCTACAAAAGACGTGTCTTCCTTCCAGTTAACTTGAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.