Basic Information
VIS ID
TVIS10001794
Fusion event
HBV-LOC105375751 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
128005677/126993432 (Hg38)
End
128005677/126993432 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
LOC105375751
Nearest miRNA
hsa-mir-12123/Upstream/2171374; hsa-mir-10400/Downstream/802530;
Nearest TSS
ENST00000518652/Upstream/2591; ENST00000645130/Downstream/16096;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/434907, chr8-CpG: 29/Downstream/322210
Nearby gene
LRATD2(-434966) ; PCAT1(+19722) ;
Upstream sequence
AGGGTGGTGAGGAACTGGTAGGATGATCATTCCTAAAATTGGATTGGATGACATAGCCCTGTGGAGTATGCTGCGTGATGGCCAGAATACCCTTGGGTAT
Downstream sequence
CATGTGCTTCTACCGCATCTTATCAGCACTCAGGCAAGGTTTACTAATATGTATAATCACAATGACTTCCAAAGGTTCCACCTTGGTACTTCTGTTAATt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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