Basic Information
VIS ID
TVIS10001799
Fusion event
HBV-CFAP46 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
134744574/132931070 (Hg38)
End
134744574/132931070 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
CFAP46
Nearest miRNA
hsa-mir-107/Upstream/1968402; hsa-mir-202/Downstream/316441;
Nearest TSS
ENST00000439456/Upstream/14388; ENST00000461291/Downstream/11473;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/3541, chr10-CpG: 120/Downstream/11089
Upstream sequence
GGGCCTCCCTACACTCCCCACACAGAGCCTGGGCCTTCCTCCTCCACAAACAAAACCTGGGCCTCCCCACACTCCCCACACAGAGCCTGGGCCTCCCTCC
Downstream sequence
TCTCCACACAGAGCCTGGGCCTCCCCACACTCCCCACGCAGAGCCTGGGCCTTCCCCACACTCCCCACGCAGAGCCTGGACCTTCCTCCTCGCCACACAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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