KYNU _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001804
Fusion event
HBV-KYNU integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
143627932/142870363 (Hg38)
End
143627932/142870363 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA2S
Target gene
KYNU
miRNAs that regulate target gene
hsa-mir-499b-5p ; hsa-mir-361-5p ; hsa-mir-4494 ; hsa-mir-2115-3p ; hsa-mir-3074-3p ; hsa-mir-4789-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4789-5p
Nearest miRNA
hsa-mir-128-1/Upstream/2283678; hsa-mir-10b/Downstream/6459915;
Nearest TSS
ENST00000437798/Upstream/738662; ENST00000410015/Downstream/7135;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/739379, chr2-CpG: 111/Downstream/1066400
Upstream sequence
ggcaggagaatggcatgaacccgggaggcggagcttgcagtgagccgagatcccgccactgcactccagcctgggcgacagagcgagactctgtctcaaa
Downstream sequence
aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaatattaaCTTGTATATTCACTATATATTCCAGTATTTTTTCCCAGTTTGTCATTTGT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate