Basic Information
VIS ID
TVIS10001806
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q35
Reference genome
GRCh37/hg19
Start
145611251/145914158 (Hg38)
End
145611251/145914158 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10399/Upstream/2531358; hsa-mir-153-2/Downstream/1463859;
Nearest TSS
ENST00000635602/Upstream/232789; ENST00000637105/Downstream/201844;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1077998, chr7-CpG: 70/Downstream/202024
Nearby gene
TPK1(-1078105) ; CNTNAP2(+202202) ;
Nearest cancer related gene
CNTNAP2(TSG, +202202) ;
Upstream sequence
tttgtgtcttctcccccagttcttagttaaccttgcttgaagtttattgatcttattgatctttccagtgaattagcttttagcttcattgattttctta
Downstream sequence
AATCTTTACTATGCTTTTCTTACTTGTAAGGCTCTTTTCTTCTCTTTAGTTTCCTACAGGATAATAAGAATGCAGATTTCTTAGCTGACTGATAAGCAAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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