PARD3B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001820
Fusion event
HBV-PARD3B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
206153617/205288893 (Hg38)
End
206153617/205288893 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
PARD3B
miRNAs that regulate target gene
hsa-mir-6873-3p ; hsa-mir-3941 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6758-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3180-5p ; hsa-mir-4642 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-4267
Nearest miRNA
hsa-mir-10b/Upstream/16155782; hsa-mir-1244-1/Downstream/1494341;
Nearest TSS
ENST00000437798/Upstream/185201; ENST00000465890/Downstream/4599;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/742706, chr2-CpG: 91/Downstream/392986
Upstream sequence
TTCAAGGATATGACCCACATCATGCATAAAGTCTTACTCAGTGACTTAAAGTCACACTGTGCTTTCTTTTCTCTGACTTCTGCAAGCCTAAAATACTCCA
Downstream sequence
GCCCTTAACTGTGCTCTATGTCAGCATTCTTGGTACGTGGTTTGCAGAGATACCTGCTGgccagtgatcccaaaagtccatgaccttgtctgatttgtaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate