Basic Information
VIS ID
TVIS10001856
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p11.12
Reference genome
GRCh37/hg19
Start
48859359/48837807 (Hg38)
End
48859359/48837807 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/740949; hsa-let-7a-2/Downstream/7906066;
Nearest TSS
ENST00000527297/Upstream/349090; ENST00000332682/Downstream/189694;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/856189, chr11-CpG: 17/Downstream/42338
Nearby gene
OR4A47(-348085) ; TRIM49B(+193793) ;
Upstream sequence
ggagcactttgaggactatggtagaaaaggaagtatcctcatataaaaactagacagaaacattatcagaaactacattgtgatgtgtgcattcaagaca
Downstream sequence
cagagtagaaccttccttttgacagagcagttttgaaacactctttttgtagaatctgcaagtggatgtttgaaacgctttgaggcctgcagtggaaacg
Target sequence
AGCCTCATAACCACTTATTCAGTTACAGGTGGAAAATTTTAAAAATCTGAAAGTCAATGTAGCAATACTAATACTAACACAAGATAGTTTAGAAAAATGAAGCCCTTTTAGTTTGATGTTTTTAAAATTTCTCTAAAGATGATTACCTTGGTTTTGCTAAAGTTTATGTAGTTGGTTCCAAGATGTGCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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