Basic Information
VIS ID
TVIS10001862
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p11.12
Reference genome
GRCh37/hg19
Start
48961136/48939584 (Hg38)
End
48961136/48939584 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/842726; hsa-let-7a-2/Downstream/7804289;
Nearest TSS
ENST00000527297/Upstream/450867; ENST00000332682/Downstream/87917;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/38394, chr11-CpG: 25/Downstream/29040
Nearby gene
OR4A47(-449862) ; TRIM49B(+92016) ;
Upstream sequence
tatttccttttctaccataggcctcaaagcacgccaaatatccacttgcagattctacaaaaagagtgtttcaaaactgctctgtcaaaagcaaggttca
Downstream sequence
actctgtgagttaaatgcccacagaacaatgttttttctgataatgcttctgtccagattttatgtgaaggtatacccatttccaatgaaggcctcaaag
Target sequence
agaatgggagaaaaattttgcaatctatccatctgataaaaggctaatatccagaatctacgaagaacttaaagaaatgtacaagaaaaaaacaaccccatcaaaaagtgggcaaaggatatgaacagacacttctcaaaagaagacatttatgcagccaacaaacatatgaaataaagctcatcatcactgctcactagagaaatgcaaattaaaaccacaacaatgagataccatgccagttagaatggcgat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate