Basic Information
VIS ID
TVIS10001867
Fusion event
HBV-TRIM48 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q11
Reference genome
GRCh37/hg19
Start
55025032/55257556 (Hg38)
End
55025032/55257556 (Hg38)
Location type
Promoter
Target gene
TRIM48
Nearest miRNA
hsa-mir-129-2/Upstream/7160698; hsa-let-7a-2/Downstream/1486317;
Nearest TSS
ENST00000527297/Upstream/550724; ENST00000417545/Downstream/4626;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/4958955, chr11-CpG: 94/Downstream/615036
Upstream sequence
tatttccttttataccatatgtctcaaagcactccaaatattcacttgccaattctacaaaaagagtgtttcaaaactgctctgtcaaaaggaaggttca
Downstream sequence
actctgtgagttgaaagcacccatctcaaagaagtttctgagaatgcttctgtctagttttcttatgaagatatttcattttctaccacaggcctcaaaa
Target sequence
gagaaaatttttgcaatctatccatctgacaaagggctaatatccagaatctacaaagaacttaaacaaattaacaagaaagaaacaaccccatcaaaaagtgggcaaaggacatgaacagacacttctcaaaagaagacatttatgcggccaacaaacatgaaaaaaaaagctcatcatcactgttcattaaagaaatgcacattaaaaccacaatgagataccatctcatgccagttagaatggcaattatta
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate