Basic Information
VIS ID
TVIS10001878
Fusion event
HBV-LOC105369363 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68051170/68283702 (Hg38)
End
68051170/68283702 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
LOC105369363
Nearest miRNA
hsa-mir-10392/Upstream/238745; hsa-let-7a-2/Downstream/799474;
Nearest TSS
ENST00000527297/Upstream/11701; ENST00000528890/Downstream/28907;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/11290, chr11-CpG: 176/Downstream/28635
Nearby gene
C11orf24(-11701) ; LRP5(+28938) ;
Upstream sequence
gcaagctctgcctcccaagttcacgttattctgcctcagcctcctgagtagctgggaccacaggcgcctgccaccacacctggctaattttttttgtatt
Downstream sequence
tttagtagagatggggtttcaccatgttagccaggatggtctcgatctcctgacctcatgatccacccgccttggcctcccaaagtgctgggattacagg
Target sequence
ACCCCAAATTGAGACTCAGCTCACTGCCTACTGACTCAGCTCACCAGAGTCTTGCTGCCGGCCCCTCCACTTCCTCTTCTTTGCTATTGCAGGGTGGCAGGTTGAGTTGAGAACAGTTGCTTACAAAGTGAGCAATCCCCTTCCAAGCCAGCCTGCCTCTGTCTCTTTGATTCTACCAGTAATTGAGCTTTGTGTTTCCCCATGGGCTCATGTATCTTTCAGCAAGGTTTTAAAGTGCTTTTCCTCTCCAGCAGT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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