Basic Information
VIS ID
TVIS10001883
Fusion event
HBV-FAM92A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
94735401/93723173 (Hg38)
End
94735401/93723173 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
FAM92A
miRNAs that regulate target gene
hsa-mir-708-5p
Nearest miRNA
hsa-mir-12123/Upstream/693334; hsa-mir-10400/Downstream/192849;
Nearest TSS
ENST00000518652/Upstream/3599; ENST00000520363/Downstream/2675;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/22056, chr8-CpG: 44/Downstream/17574
Upstream sequence
TACCAAAGAGTGAGTGAGACATCTAAACAAAACATTGCATGTGGAAGACCTAAAGAGGAAACCTGGGAACTCATTATTTACTTATTTTAATAATTTACAG
Downstream sequence
ttttagtagagatggggtttcaccatgttagccaggatggtctcgatctcctgacctcatgatccgcccgccttggcctcccaaagtgctgggactgcag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate