hsa-mir-187-5p _LIHC.png
hsa-mir-548ar-3p _LIHC.png
hsa-mir-130b-3p _LIHC.png
DDX6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001889
Fusion event
HBV-DDX6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
End
118647385/118776676 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-877-3p ; hsa-mir-505-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-145-5p ; hsa-mir-143-3p ; hsa-mir-218-5p ; hsa-mir-2909 ; hsa-mir-4477b ; hsa-mir-2053 ; hsa-mir-5089-3p ; hsa-mir-1296-5p ; hsa-mir-582-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-139-5p ; hsa-mir-4277 ; hsa-mir-6834-3p ; hsa-mir-5584-3p ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-759 ; hsa-mir-6868-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-3613-3p ; hsa-mir-6074 ; hsa-mir-548m ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-19a-3p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-4525 ; hsa-mir-5010-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-3175 ; hsa-mir-6134 ; hsa-mir-6878-5p ; hsa-mir-558 ; hsa-mir-4311 ; hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-587 ; hsa-mir-302c-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-4540 ; hsa-mir-3124-3p ; hsa-mir-554 ; hsa-mir-6501-3p ; hsa-mir-6838-3p ; hsa-mir-646 ; hsa-mir-4520-3p ; hsa-mir-6882-3p ; hsa-mir-4638-3p ; hsa-mir-335-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4272 ; hsa-mir-22-3p ; hsa-mir-3654 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-4653-3p ; hsa-mir-3924 ; hsa-mir-130a-3p ; hsa-mir-28-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-3688-5p ; hsa-mir-4295 ; hsa-mir-4302 ; hsa-mir-4524a-3p ; hsa-mir-454-3p ; hsa-mir-545-3p ; hsa-mir-644a ; hsa-mir-885-3p ; hsa-mir-891a-3p
Nearest miRNA
hsa-mir-10392/Upstream/132597; hsa-let-7a-2/Downstream/134032;
Nearest cancer related gene
DDX6(OG, No orient, 0)
Upstream sequence
gtaatcccaacactttgggagactgaagcaggcagatcacaaggtcaggagatcgagaccatcctggctaacatggtgaaaccccatctctactaaaaca
Downstream sequence
caaaaaattagccgggtgctgtggtgcacgcctgtagtccccgctattcgggaggctgaggcaggggaatcgcgtgaacccaggagtcggagattgcagt
Target sequence
ATGGCATCTTAACCTTGCAAATTCATGAATATAGGCACCAAAAAGCTAAACAATTTGCCAATCATGGTAGGAGAACTGGTAGCATGAAAAGACAGAGATGGTAAATGAGACTCAGATGGTCAATAATAATCataaaagcaaacatttagatattttatagtagctcctatgagtaggcaatgtgctaagcattgtcatgtgttacctggcttaattttcagaatgatgctatgggagagatacCttttttttttt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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