Basic Information
VIS ID
TVIS10001892
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
123717339/123846631 (Hg38)
End
123717339/123846631 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/465119; hsa-mir-3167/Downstream/3141827;
Nearest TSS
ENST00000527297/Upstream/40244; ENST00000321355/Downstream/39002;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/104794, chr11-CpG: 44/Downstream/776137
Nearby gene
OR6M1(-40282) ; TMEM225(+36294) ;
Upstream sequence
AAGAATTTTGATTTGGTAATGAATCAAGACATTAGACACGACTGAATTAAGCATAGGTCCTTGACTTCTATTTTAGATCACTGGTAAAATGATCGAAAGC
Downstream sequence
TTCTGAACTCTCAATTATTTTTTCAGCAGTAGGAATGTAATTTCCTGTCTATCCAGTCGATTTCTATTTCTTCAGTGGATCCATCCAGAAAATTGAAGTT
Target sequence
tatcttcagtaatatactacaacctaatttagtatgtaaacaaactgaagcctcattaaaagtattttattttttatttttatttttggtaattggctgagtctcagccaatggcagcagccaaccttcagccaattgtcagtggccagcggatcagactatatccaaataaggcaaccagggaattataaccagttaagctgtttctctgtctcacttatgttgtctgtttgtgaatgcttcccgtccatattg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate