ACTR3C _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001903
Fusion event
HBV-ACTR3C integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
149709581/150012492 (Hg38)
End
149709581/150012492 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
ACTR3C
miRNAs that regulate target gene
hsa-mir-379-3p ; hsa-mir-487a-3p ; hsa-mir-127-3p ; hsa-mir-539-3p
Nearest miRNA
hsa-mir-10399/Upstream/2634371; hsa-mir-153-2/Downstream/1225929;
Nearest TSS
ENST00000635602/Upstream/11740; ENST00000493400/Downstream/28029;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/138192, chr7-CpG: 189/Downstream/34821
Nearby gene
ATP6V0E2(-131794) ; ACTR3C(+234720) ;
Upstream sequence
AAAGCCACAAATCTTAAGAAAATACATGTTTAACTGAAATTATAAAGATATTTTGCAAAAAAGGGAAATCGCTCCTGCTGGTGTTTTGTGTATAAATCTC
Downstream sequence
ttttagtagagatggggtttcaccatgttagccaggatggtctcgatctcctgacctcatgatcctcccgcctcggcctcccaaagtgctgggattacag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate