Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001907
Fusion event
HBV-IGF2R integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
End
160521779/160100747 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-657 ; hsa-mir-155-5p ; hsa-mir-9-5p ; hsa-mir-26b-5p ; hsa-mir-1271-5p ; hsa-mir-423-3p ; hsa-mir-128-3p ; hsa-mir-211-5p ; hsa-mir-545-5p ; hsa-mir-412-3p ; hsa-mir-377-3p ; hsa-mir-218-5p ; hsa-mir-96-3p ; hsa-mir-2681-3p ; hsa-mir-548m ; hsa-mir-8485 ; hsa-mir-7977 ; hsa-mir-4284 ; hsa-mir-24-3p ; hsa-mir-564 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-383-3p ; hsa-mir-342-3p ; hsa-mir-6777-3p ; hsa-mir-6089 ; hsa-mir-561-5p ; hsa-mir-6715b-3p ; hsa-mir-4742-3p ; hsa-mir-6715a-3p ; hsa-mir-1178-5p ; hsa-mir-649 ; hsa-mir-106a-3p ; hsa-mir-1296-5p ; hsa-mir-6877-5p ; hsa-mir-4480 ; hsa-mir-5008-5p ; hsa-mir-3146 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4512 ; hsa-mir-6895-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-1247-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-3612 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4756-3p ; hsa-mir-5186 ; hsa-mir-5694 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-4252 ; hsa-mir-4719 ; hsa-mir-551b-5p
Nearest miRNA
hsa-mir-10398/Upstream/1335994; hsa-mir-1913/Downstream/6408607;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/9314, chr6-CpG: 55/Downstream/32882
Nearest cancer related gene
IGF2R(TSG, No orient, 0)
Upstream sequence
ggtgtgaacccaggagacagagcttgcagtgagccaagatggcaccactgcactactgtactccagcctgggtgacaaagcgagactccgtctcaaaaaa
Downstream sequence
ttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttggagacagagacttgctcttttgcccaggctggagtgcag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.