Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10001966
Fusion event
HBV-ASPA integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
Start
End
3390842/3487548 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-203a-3p ; hsa-mir-100-3p ; hsa-mir-551b-5p ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6795-3p ; hsa-mir-6826-3p ; hsa-mir-6887-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-3622b-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-4327 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-4728-5p ; hsa-mir-4768-3p ; hsa-mir-490-3p ; hsa-mir-5197-5p ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6808-5p ; hsa-mir-6883-5p ; hsa-mir-6893-5p ; hsa-mir-7106-5p ; hsa-mir-7851-3p ; hsa-mir-940
Nearest miRNA
hsa-mir-1253/Upstream/739366; hsa-mir-10226/Downstream/1482154;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/15605, chr17-CpG: 18/Downstream/45111
Upstream sequence
ACATATCAGCAATGTTTGTTCTGGCTAAGAGTAGCATTGCCTACAAATATCATAGCCTAAGATTGATATTTGAGAGTTTGGAAATCTTAAGCTTTTATTT
Downstream sequence
GGTGTCACAGAGAAACAGGATCTGTATCTCTTATTGCTAAGCCTTTGATTTGTTTCAGCTAATTGCCTGTATTTGGATATTTAGCTTACTCTAATTCCTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.