Basic Information
VIS ID
TVIS10001973
Fusion event
HBV-chr9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
7233279/7233279 (Hg38)
End
7233279/7233279 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/1225375; hsa-let-7a-1/Downstream/11340027;
Nearest TSS
ENST00000422679/Upstream/105372; ENST00000430766/Downstream/553409;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/474407, chr9-CpG: 43/Downstream/566076
Nearby gene
KDM4C(-57631) ; DMAC1(+563212) ;
Nearest cancer related gene
KDM4C(OG, -57631) ;
Upstream sequence
GGGGAAAATAATGCTAATGAATTCTTGAAATATTACCTTTTTAAGCAAATTCCTTTTAAATATTGGAGATATTATAGTAAGAGAAATACAGCAGGGAAAG
Downstream sequence
GTATAGCAGCTGTGATCTGCTGGTTAAGTAGTCAACCTCATCACCTAGCATGACGCTGTGTAAGAGAGAAGAATATGGGATCTCATGCACTGTTTCAACA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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