Basic Information
VIS ID
TVIS10001974
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
27873654/27852107 (Hg38)
End
27873654/27852107 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/337060; hsa-let-7a-2/Downstream/204708;
Nearest TSS
ENST00000527297/Upstream/130049; ENST00000403099/Downstream/167468;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/129090, chr11-CpG: 25/Downstream/258209
Nearby gene
BDNF(-130049) ; KIF18A(+168509) ;
Upstream sequence
ccctcccttcccctcccttcccctcccttcccctcccttcccctcccttcccctcccctcccctctcctctcctctctttccttccttccttccttcctt
Downstream sequence
ccttccttccttccttccttccttccttccttccttcATCTAGCCTGATCAGATCAGAGTAGATTATCTGGCTTGAAAAAGACCAAATAATAAATATTTC
Target sequence
taaagtcattgaatttttcaaagcaaccctaagaggtacaggttagtattatgtccattttacagataagaggactgaggaacagaatgggaccatagctattaaatgggaaaggaagacgaatttgaacccagCCCGCATTCTTTATCCCTTATTGCCTCTTATATAGTaaagagcattggactgagaataaggaaatatttgttctagtttagggctgcttctcataactgtgtgccctGTCTTTAAAATTCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate