Basic Information
VIS ID
TVIS10002015
Fusion event
HBV-PRSS43P integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
46816063/46774573 (Hg38)
End
46816063/46774573 (Hg38)
Location type
Intronic
Target gene
PRSS43P
Nearest miRNA
hsa-mir-12127/Upstream/1912592; hsa-let-7g/Downstream/1074982;
Nearest TSS
ENST00000440867/Upstream/29818; ENST00000490109/Downstream/37985;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/17600, chr3-CpG: 32/Downstream/37664
Nearby gene
PRSS45P(-29818) ; PRSS42P(+55831) ;
Upstream sequence
gaggcgggagaattgcttgaacctgcgaggcagaggttgtggtgagctgagatcacaccactgcactccagcctgggcagcagagcaaaactctgctaaa
Downstream sequence
ttattggtctattcagagattcaacttcttcctggtttagtcttgggagagtgtatgtgtcgaggaatttatccatttcttctagattttctagtttatt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate