DOCK9 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002024
Fusion event
HBV-DOCK9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
99597245/98944991 (Hg38)
End
99597245/98944991 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
DOCK9
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-32-5p ; hsa-mir-16-5p ; hsa-mir-214-3p ; hsa-mir-218-5p ; hsa-mir-4477a ; hsa-mir-889-3p ; hsa-mir-1295b-3p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-1277-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1297/Upstream/736391; hsa-mir-1267/Downstream/411140;
Nearest TSS
ENST00000623511/Upstream/56306; ENST00000562781/Downstream/32999;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/192142, chr13-CpG: 222/Downstream/141086
Upstream sequence
GGCATAGAAGATATTTTTCAGAAGCAGTTTTCATCTTTAACACTTCCTTCAGTTTAGGAAAATAACACTGAATTTGCACAGTCCAATGCTGATCTTCTTG
Downstream sequence
AAGTTTGGTGAGCTAAGCAAGATGGTTTTAAACAAATTAAAGAACAAATGAATCAGTCAAGGAAACAATGATTCTAAATGTTTGTAAATCACTTCCTTTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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