Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002041
Fusion event
HBV-TRIP13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
Start
End
913153/913038 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-570-3p ; hsa-mir-3121-3p ; hsa-mir-4635 ; hsa-mir-885-5p ; hsa-mir-4800-5p ; hsa-mir-3138 ; hsa-mir-711 ; hsa-mir-4252 ; hsa-mir-7114-5p ; hsa-mir-4318 ; hsa-mir-328-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-6795-5p ; hsa-mir-6825-5p ; hsa-mir-6870-5p ; hsa-mir-6885-5p ; hsa-mir-6887-5p ; hsa-mir-7106-5p ; hsa-mir-7109-5p ; hsa-mir-7111-5p ; hsa-mir-766-5p ; hsa-mir-7706
Nearest miRNA
hsa-mir-10397/Downstream/149858;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/292, chr5-CpG: 77/Downstream/13433
Upstream sequence
CCAGAAGAGGAACCGTGTCTTATTCTGTCAAATGAATGAATAAATAAACGGATGAATCCCAACGTGTTATTACTGAGGAGGACAAACATAATAATCTTAG
Downstream sequence
GTCAGCACTGTCCAGGCATGGTTTTCTTGGGGGTTGGGGAAAGGAGACGGAGCTCTGTGGAGCTTTGCCTGGAGAATGCCAGTGATCTGAAGACTGATTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.