MED9 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002043
Fusion event
HBV-MED9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
17375840/17472526 (Hg38)
End
17375840/17472526 (Hg38)
Location type
Promoter
Target gene
MED9
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-1253/Upstream/1190438; hsa-mir-10226/Downstream/340954;
Nearest TSS
ENST00000595228/Upstream/127257; ENST00000585041/Downstream/4460;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/88468, chr17-CpG: 23/Downstream/4335
Upstream sequence
CGTAATGGAGTATCTCAGAGTTAGGAGAGGACGGCTGAAAAGAATAAAAAGGAGATTCAAGTGGAGCTCAGAGAGAGAAGAAAGACAATCCGCAGGGTGG
Downstream sequence
ACCCAAGCAAAGGGCTTTTGTCTGAGGTTTATGCAATGAATCGTGGCTTCAGTGAGCTGATTCCTGGTATACATTGCACTACATTTGGCCAGAACAATGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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