Basic Information
VIS ID
TVIS10002059
Fusion event
HBV-EPCAM-DT integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
47429731/47202592 (Hg38)
End
47429731/47202592 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
EPCAM-DT
Nearest miRNA
hsa-mir-1301/Upstream/11731106; hsa-mir-10b/Downstream/175083;
Nearest TSS
ENST00000437798/Upstream/25991; ENST00000444361/Downstream/23202;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/25626, chr2-CpG: 35/Downstream/69733
Upstream sequence
gcagcacaccagcatggcacatgtgtacatatgtaactaacctgcacattgtgcacatgtaccctaaaacttaaagtataataataataaaaTTaaaaaa
Downstream sequence
aagaagaagaaaaaaaaaaagaagtgcttgatcaaaaaaaaaaaaaagaaagaaagaaaaaataaaaTAGAGTCTAGTGATTGTGGGCAAAAATAAATAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate