Basic Information
VIS ID
TVIS10002079
Fusion event
HBV-LOC105370826 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
53713362/53421165 (Hg38)
End
53713362/53421165 (Hg38)
Location type
Intronic
Target gene
LOC105370826
Nearest miRNA
hsa-mir-10393/Upstream/1143965; hsa-mir-11181/Downstream/1951775;
Nearest TSS
ENST00000557528/Upstream/304800; ENST00000561210/Downstream/119915;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/614886, chr15-CpG: 33/Downstream/338293
Nearby gene
ONECUT1(-631153) ; WDR72(+92576) ;
Upstream sequence
CCAGCTTGAGCTCTGACATAGTTTCATATGGGGATTCAGGTAGAGGTGTATTTGTGAGCTTCTGACACCTTCCAGAAGGTCAAATCACACAATTAAAATA
Downstream sequence
TTCTATTGCAAATGATGCATGGGTTTCAAAACTATTAATATATTTGCAAGACAAAACAAGGCTGCAAGTAATTACTTGTGTACTCTTTAATTTGTTGCAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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