Basic Information
VIS ID
TVIS10002084
Fusion event
HBV-chr9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
24811430/24811432 (Hg38)
End
24811430/24811432 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/3299247; hsa-let-7a-1/Downstream/4052194;
Nearest TSS
ENST00000422679/Upstream/265434; ENST00000627303/Downstream/867008;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/959908, chr9-CpG: 111/Downstream/866064
Nearby gene
IZUMO3(-265756) ; TUSC1(+864957) ;
Nearest cancer related gene
TUSC1(TSG, +864957) ;
Upstream sequence
accccaacccaaccctaaccctaaccctaacccaaccctaaccctaaccctaacccaaccctcaccctcaccctcaccctcaccctcaccctcaccctca
Downstream sequence
taaaattattagaactaatgaataagcaaagtggcaggatacaagatcaatattaaatatcaaatgtatttctatgcactagcaagagaaaattcaataa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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