Basic Information
VIS ID
TVIS10002118
Fusion event
HBV-FGF7P6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q13
Reference genome
GRCh37/hg19
Start
46685365/62374064 (Hg38)
End
46685365/62374064 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA9F
Target gene
FGF7P6
Nearest miRNA
hsa-mir-101-2/Upstream/21140229; hsa-let-7a-1/Downstream/8435911;
Nearest TSS
ENST00000422679/Upstream/22528; ENST00000428440/Downstream/2062;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/383677, chr9-CpG: 27/Downstream/176551
Upstream sequence
CGGGGTCCTCTGTGGAACTGGCTTCCGGCCCCATGCTGACAGGGCCCGGACCCGCTGTGCTCAGGCTCAGAGAACCATCGCCAACAGCACAGGCTGACGG
Downstream sequence
cctgccttggcctcccaaagtgctgggattacatgcatgagccatcgtgccttgcccgattttttttttttttttttttttttaagaaactgaagcctct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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