Basic Information
VIS ID
TVIS10002136
Fusion event
HBV-chr14 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
61135190/60668472 (Hg38)
End
61135190/60668472 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA14B
Nearest miRNA
hsa-mir-208a/Upstream/19761; hsa-mir-1185-1/Downstream/3426552;
Nearest TSS
ENST00000550708/Upstream/10213; ENST00000555545/Downstream/54693;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/10577, chr14-CpG: 209/Downstream/52926
Nearby gene
SIX1(-19035) ; SIX4(+41066) ;
Nearest cancer related gene
SIX1(OG, -19035) ;
Upstream sequence
tatactatacagccttaaaaaagaaggaaatcttgtcatttgcaacaacatggatgaacccggagcacattatgctaagtgaaataaagcaggcacagaa
Downstream sequence
gacaaatactgcacaatctcactaaaatctgtgaaatctgaaaaagtcaaactcatagaaacagagtagaatggtggttgctagaggctgggagggcgag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate