Basic Information
VIS ID
TVIS10002146
Fusion event
HBV-chr14 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38345961/37876756 (Hg38)
End
38345961/37876756 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/924365; hsa-mir-1185-1/Downstream/9884239;
Nearest TSS
ENST00000550708/Upstream/49455; ENST00000553887/Downstream/25368;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/253785, chr14-CpG: 43/Downstream/331193
Nearby gene
FOXA1(-281636) ; SSTR1(+331243) ;
Nearest cancer related gene
FOXA1(TSG, -281636) ;
Upstream sequence
CCATAGCAAATGATGCTCATTCTTTGAAAACAAGCCTCTGGTGTATAAACTATAAGGATAGTTTTATCCAGGCATAAAGCAGAGAGAGTGATACCAGTTC
Downstream sequence
ATGCCTGGATAGAATTATTGGAAAGGGGAGTTCAAAGACAGAATTCTGCTTTGACAAGAAGAATTTCAAAATATGACTTTGCCCCCCAAAAATTTTACTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate