Basic Information
VIS ID
TVIS10002157
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
87268070/86255841 (Hg38)
End
87268070/86255841 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/6014368; hsa-mir-10400/Downstream/4949644;
Nearest TSS
ENST00000518652/Upstream/25460; ENST00000523863/Downstream/65305;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/186024, chr8-CpG: 100/Downstream/86474
Nearby gene
SLC7A13(-25466) ; WWP1(+86924) ;
Upstream sequence
TGCTCTTGCTAGCTGTGCCATGAACATCTTGAAGCTAAGAGCTGGTGAAGAGCACATGGGCCACACCCCTGCAGCCAGAATGACTCCTGTACAGACCTTT
Downstream sequence
ATTGGGCACAAAGGTTTACTTATACAAACATTGATTTTAAAATCAGAGATCTTTCAACTATGTTGTCCTTGAACTTTGGAATCTGGTTAAATAATGTCTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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