Basic Information
VIS ID
TVIS10002161
Fusion event
HBV-chr20 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
11909683/11929035 (Hg38)
End
11909683/11929035 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/1279340; hsa-mir-1-1/Downstream/6541580;
Nearest TSS
ENST00000382410/Upstream/7469; ENST00000432244/Downstream/315261;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/37476, chr20-CpG: 217/Downstream/1290988
Nearby gene
BTBD3(-2440) ; SREBF2-AS1(+936169) ;
Upstream sequence
GCACCCCTTATAATTGTGTTGATACAGTGCATTGAACGTTAATCAATTCAAAATTAAAGGCTGTCGTAGCTCTTCAGTCTTCAAGAAAAAGTCCAAGAAC
Downstream sequence
ATTTGGAGGCATTAATGGACTGAAGAATATATTGGTTTTTTGCATAATTGAGTTCCCTAGAAGAGACAGAAGGTTTAATGAATCATTCAAGGGATCAACC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate