Basic Information
VIS ID
TVIS10002179
Fusion event
HBV-chr15 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
88161993/87618762 (Hg38)
End
88161993/87618762 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/1793032; hsa-mir-11181/Downstream/327444;
Nearest TSS
ENST00000557528/Upstream/41833; ENST00000569588/Downstream/85090;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/1777878, chr15-CpG: 36/Downstream/636661
Nearby gene
LINC00052(-39076) ; NTRK3(+257995) ;
Nearest cancer related gene
NTRK3(OG, +257995) ;
Upstream sequence
TTCAGGACAGATGTCAACTTTGAATTTAAGCATTTTCTGTTATTTACTATACCCCATCTAGGCATAGCTAACTATAATGGtcaaaatatttaaaaactac
Downstream sequence
tatggcacacagaccagccaattagaacagataaataaccagtatggttgtactgagggttaggaggggcagtgaatatcagttctgGGACTGTCATTTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate